METHANESULPHONYL CHLORIDE FOR SYNTHESIS 99%
SKU
RXSOL-60-6604-952
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Category
Variations
Methanesulfonyl chloride can be used for the mesylation of primary alcohols to synthesize the corresponding methanesulfonates. It may also be used for the conversion of amines to the corresponding sulfonamides.
Note
rylsulfonyl chlorides are made industrially in a two-step, one-pot reaction from the arene and chlorosulfuric acid: C6H6 + HOSO2Cl → C6H5SO3H + HCl. Phenyldiazonium chloride reacts with sulfur dioxide and hydrochloric acid to give the sulfonyl chloride:
The main use of methanesulfonyl chloride is the formation of methanesulfonates from alcohols and a non-nucleophilic base. Methanesulfonates are used as intermediates in substitution reactions, elimination reactions, reductions, and rearrangement reactions.