Title
Tert BUTYLDIMETHYLSILYL CHLORIDE FOR SYNTHESIS
SKU
RXSOL-60-6605-663
Supply Location::
Locations
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Category
Lab Chemical-60
SHORT DESCRIPTION:::
PRODUCT REMARK:::>
TAG IDENFIFICATION:::
FIELD NOTE:::
Tert BUTYLDIMETHYLSILYL CHLORIDE FOR SYNTHESIS is used to protect alcohols in organic synthesis. Examples can be found in the Nicolaou taxol total synthesis
Note
tert-Butyldimethylsilyl chloride is an organosilicon compound with the formula Me₂SiCl. It is commonly abbreviated as TBSCl or TBDMSCl. It is a silane containing two methyl groups, a tert-butyl group, and a reactive chloride.
Application
The compound is used to protect alcohols in organic synthesis. Examples can be found in the Nicolaou taxol total synthesis. tert-Butyldimethylsilyl chloride reacts with alcohols in the presence of base to give tert-butyldimethylsilyl
