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Thiamine is used to treat thiamine deficiency which when severe can prove fatal. In less severe cases, non-specific signs include malaise, weight loss, irritability and confusion.
License data: US DailyMed: Thiamine; US FDA: ...
Other names: Vitamin B1, aneurine, thiamin
Thiamin(e), also known as vitamin B1, is now known to play a fundamental role in energy metabolism. Its discovery followed from the original early research on the ‘anti-beriberi factor’ found in rice polishings. After its synthesis in 1936, it led to many years of research to find its action in treating beriberi, a lethal scourge known for thousands of years, particularly in cultures dependent on rice as a staple.
Vitamin B1, thiamin, or thiamine, enables the body to use carbohydrates as energy. It is essential for glucose metabolism, and it plays a key role in nerve, muscle, and heart function. Vitamin B1 is a water-soluble vitamin, as are all vitamins of the B complex.
The RDA of thiamine is 1–1.5 mg per day, but only in a biochemically healthy individual, and many physicians are under the impression that this kind of vitamin deficiency, if it occurs at all, is easily and quickly treated.