Title
ETHYL TRI FLUORO ACETATE
SKU
RXSOL-60-6604-569
Supply Location::
Category
Lab Chemical-60
SHORT DESCRIPTION:::
PRODUCT REMARK:::>
TAG IDENFIFICATION:::
FIELD NOTE:::
Ethyl trifluoroacetate is used as an intermediate in organic synthesis to prepare organic fluorine compounds like 3-ethyl-1-methylimidazolium trifluoroacetate (EMITA). It is involved in the syntheses of various pharmaceutically active molecules and agricultural products.
Note
- Moisture Sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and strong acids.
Application
- Ethyl trifluoroacetate can be used:
- To synthesize cyclopentenones or furans containing trifluoromethyl group from aromatic ynones.
- In the selective trifluoroacetylation of anilines catalyzed by 4-dimethylaminopyridine.
- As a starting material in the two-step electrosynthesis of trifluoroacetyltrimethylsilane (CF3COSiMe3).
- In the preparation of trifluoromethyl ketones via trifluoroacetic ester/ketone metathesis with alkyl aryl ketones.
- To synthesize o-fluorinated trifluoro acetophenones from substituted fluorobenzene.
