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SURAT CHEMICAL TAG:
D-Serine is a non-essential amino acid and dextro isomer of serine with antipsychotic activity. D-serine is a selective full agonist at the glycine site of N-methyl-D-aspartate (NMDA)-type glutamate receptor. Hypofunction of NMDA type of neurotransmission is believed to play a major role in pathophysiology of schizophrenia, therefore, administration of D-serine and subsequent activation of NMDA receptors may alleviate psychotic tendencies.
CAS Number 312-84-5
Synonyms NSC 77689 (R)-Serine
Molecular Formula C3H7NO3
Formula Weight105.1
Purity≥95%
Formulation A solid
Solubility PBS5 mg/mL
pH 7.2
Colour White to off-white
Appearance (Form) Crystalline compound
Solubility (Turbidity) 10% solution 2N HCl Clear
Assaymin. 99%
Specific rotation [a] -13° to -14° (C=5 ,5N HCl)
Loss on dryingmax. 0.3%
Sulphated Ash max. 0.1%
Iron (Fe) max. 0.001%
Heavy Metals (Pb) max. 0.001%
Homogeneity by TLC Passes test
D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate.
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