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D-Serin

D-Serin
SKU
RXSOL-19-3060-025
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D-Serin manufacturer supplier distributor in Mumbai, Kandla, Kolkata, Vizag, Chennai, India, Fujairah, Dubai, Sharjah, UAE, Gulf, Middle East, Muscat Oman, Kenya Africa. Get the best quality of D-Serin at a competitive price from us. We have ready stock of D-Serin in India, UAE Gulf, Oman, Kenya Africa. Contact us for bulk as well as small orders.


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D-Serine is a non-essential amino acid and dextro isomer of serine with antipsychotic activity. D-serine is a selective full agonist at the glycine site of N-methyl-D-aspartate (NMDA)-type glutamate receptor. Hypofunction of NMDA type of neurotransmission is believed to play a major role in pathophysiology of schizophrenia, therefore, administration of D-serine and subsequent activation of NMDA receptors may alleviate psychotic tendencies.

Remarks

 

CAS Number     312-84-5   
Synonyms    NSC 77689 (R)-Serine
Molecular Formula                                                          C3H7NO3
Formula Weight 105.1
Purity ≥95%
Formulation  A solid
Solubility PBS 5 mg/mL
pH  7.2
 

 

 

Colour                                                                                                       White to off-white  
Appearance (Form)  Crystalline compound
Solubility (Turbidity) 10% solution 2N HCl  Clear                                                         
Assay min. 99%
Specific rotation [a] -13° to -14° (C=5 , 5N HCl)
Loss on drying max. 0.3%
Sulphated Ash  max. 0.1%
Iron (Fe)  max. 0.001%
Heavy Metals (Pb)  max. 0.001%
Homogeneity by TLC  Passes test

D-Serine is involved in the biosynthesis of purines, pyrimidines, and other amino acids. D-Serine also is an agonist of glycine site of the NMDA-type glutamate receptor. It also acts as Lacosamide intermediate.

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